not reacting in a quick or positive way to something

Depression can make a new mother unresponsive to her baby. 抑郁症可能会导致母亲对刚生下来不久的孩子没有反应。

not reacting or moving at all because of being unconscious or very ill

The patient was collapsed and unresponsive when he was brought into hospital. 病人被送到医院时处于昏迷状态，没有反应。